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海马内注射PrP(C)抗体对APPswe/PSEN1(dE9)转基因小鼠学习和记忆的影响

OBJECTIVE: To study the effects of intrahippocampal injection of cellular prion protein (PrP(C)) antibody on cognitive deficits of APPswe/PSEN1(dE9) transgenic mice. METHODS: Eight-month-old male APPswe/PSEN1(dE9) transgenic mice were subjected to bilateral intrahippocampal injection of a single dos...

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Détails bibliographiques
Publié dans:Nan Fang Yi Ke Da Xue Xue Bao
Format: Artigo
Langue:Inglês
Publié: 南方医科大学学报编辑部 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765653/
https://ncbi.nlm.nih.gov/pubmed/29735445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-4254.2018.04.12
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