Potential role of iron in repair of inflammatory demyelinating lesions

Inflammatory destruction of iron-rich myelin is characteristic of multiple sclerosis (MS). Although iron is needed for oligodendrocytes to produce myelin during development, its deposition has also been linked to neurodegeneration and inflammation, including in MS. We report perivascular iron deposi...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Lee, Nathanael J., Ha, Seung-Kwon, Sati, Pascal, Absinta, Martina, Nair, Govind, Luciano, Nicholas J., Leibovitch, Emily C., Yen, Cecil C., Rouault, Tracey A., Silva, Afonso C., Jacobson, Steven, Reich, Daniel S.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763243/
https://ncbi.nlm.nih.gov/pubmed/31498148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126809
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