Optimizing ethambutol dosing among HIV/tuberculosis co-infected patients: a population pharmacokinetic modelling and simulation study

BACKGROUND: Reduced ethambutol serum concentrations are commonly observed among TB patients co-infected with HIV and may lead to treatment failure. OBJECTIVES: To perform a population pharmacokinetic study of ethambutol in HIV/TB patients, and to evaluate an intensified ethambutol weight-based dosin...

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Dettagli Bibliografici
Pubblicato in:J Antimicrob Chemother
Autori principali: Mehta, Krina, Ravimohan, Shruthi, Pasipanodya, Jotam G, Srivastava, Shashikant, Modongo, Chawangwa, Zetola, Nicola M, Weissman, Drew, Ivaturi, Vijay, Gumbo, Tawanda, Bisson, Gregory P, Vinnard, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753485/
https://ncbi.nlm.nih.gov/pubmed/31273386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz265
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