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Potent modulation of the CepR quorum sensing receptor and virulence in a Burkholderia cepacia complex member using non-native lactone ligands

The Burkholderia cepacia complex (Bcc) is a family of closely related bacterial pathogens that are the causative agent of deadly human infections. Virulence in Bcc species has been shown to be controlled by the CepI/CepR quorum sensing (QS) system, which is mediated by an N-acyl L-homoserine lactone...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Slinger, Betty L., Deay, Jacqueline J., Chandler, Josephine R., Blackwell, Helen E.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748986/
https://ncbi.nlm.nih.gov/pubmed/31530834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49693-x
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