Etomoxir actions on regulatory and memory T cells are independent of Cpt1a-mediated fatty acid oxidation

T cell subsets including effector (T(eff)), regulatory (T(reg)) and memory (T(mem)) cells are characterized by distinct metabolic profiles that influence their differentiation and function. Previous research suggests that engagement of long-chain fatty acid oxidation (LC-FAO) supports Foxp3(+) T(reg...

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Publicat a:Cell Metab
Autors principals: Raud, Brenda, Roy, Dominic G., Divakaruni, Ajit S., Tarasenko, Tatyana N., Franke, Raimo, Ma, Eric H., Samborska, Bozena, Hsieh, Wei Y., Wong, Alison H., Stüve, Philipp, Arnold-Schrauf, Catharina, Guderian, Melanie, Lochner, Matthias, Rampertaap, Shakuntala, Romito, Kimberly, Monsale, Joseph, Brönstrup, Mark, Bensinger, Steven J., Murphy, Anne N., McGuire, Peter J., Jones, Russell G., Sparwasser, Tim, Berod, Luciana
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747686/
https://ncbi.nlm.nih.gov/pubmed/30043753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.06.002
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