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MicroRNA-181a protects against pericyte apoptosis via directly targeting FOXO1: implication for ameliorated cognitive deficits in APP/PS1 mice

MicroRNAs (miRNAs) have emerged as critical regulators in the pathology of Alzheimer’s disease (AD). MiR-181a is associated with hippocampal memory formation and aberrantly expressed in patients with mild cognitive impairment (MCI), however, little is known about its role and underlying mechanism in...

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Bibliografische gegevens
Gepubliceerd in:Aging (Albany NY)
Hoofdauteurs: Wu, Qingbin, Yuan, Xiaochen, Bai, Jing, Han, Ruiqin, Li, Zhigang, Zhang, Honggang, Xiu, Ruijuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738434/
https://ncbi.nlm.nih.gov/pubmed/31467256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102171
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