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Similarities and differences in patterns of germline mutation between mice and humans
Whole genome sequencing (WGS) studies have estimated the human germline mutation rate per basepair per generation (~1.2 × 10(−8)) to be higher than in mice (3.5–5.4 × 10(−9)). In humans, most germline mutations are paternal in origin and numbers of mutations per offspring increase with paternal and...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6731245/ https://ncbi.nlm.nih.gov/pubmed/31492841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12023-w |
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