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Blocked O-GlcNAc cycling disrupts mouse hematopoeitic stem cell maintenance and early T cell development

Small numbers of hematopoietic stem cells (HSCs) balance self-renewal and differentiation to produce the diversity and abundance of cell types that make up the blood system. How nutrients are recruited to support this massive differentiation and proliferation process remains largely unknown. The uni...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Abramowitz, Lara K., Harly, Christelle, Das, Arundhoti, Bhandoola, Avinash, Hanover, John A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715813/
https://ncbi.nlm.nih.gov/pubmed/31467334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48991-8
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