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Downregulation of Nodal inhibits metastatic progression in retinoblastoma
Retinoblastoma is the most common intraocular malignancy in children. We previously found that the ACVR1C/SMAD2 pathway is significantly upregulated in invasive retinoblastoma samples from patients. Here we studied the role of an ACVR1C ligand, Nodal, in regulating growth and metastatic disseminatio...
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| Publicado no: | Acta Neuropathol Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6709548/ https://ncbi.nlm.nih.gov/pubmed/31451106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0785-4 |
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