Downregulation of Nodal inhibits metastatic progression in retinoblastoma

Retinoblastoma is the most common intraocular malignancy in children. We previously found that the ACVR1C/SMAD2 pathway is significantly upregulated in invasive retinoblastoma samples from patients. Here we studied the role of an ACVR1C ligand, Nodal, in regulating growth and metastatic disseminatio...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol Commun
Autors principals: Asnaghi, Laura, White, David T., Yoon, Lynn, Price, Antoinette, Lee, Grace Y., Sahoo, Arpan, Mumm, Jeff S., Eberhart, Charles G.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709548/
https://ncbi.nlm.nih.gov/pubmed/31451106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0785-4
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