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Intrathecal B-cell accumulation and axonal damage distinguish MRI-based benign from aggressive onset in MS

OBJECTIVE: We explored the incremental value of adding multiple disease activity biomarkers in CSF and serum for distinguishing MRI-based benign from aggressive MS in early disease course. METHODS: Ninety-three patients diagnosed with clinically isolated syndrome (CIS) or early MS were divided into...

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Bibliographic Details
Published in:Neurol Neuroimmunol Neuroinflamm
Main Authors: Engel, Sinah, Friedrich, Michaela, Muthuraman, Muthuraman, Steffen, Falk, Poplawski, Alicia, Groppa, Sergiu, Bittner, Stefan, Zipp, Frauke, Luessi, Felix
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705631/
https://ncbi.nlm.nih.gov/pubmed/31454774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000595
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