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Acylpeptide hydrolase is a novel regulator of KRAS plasma membrane localization and function
The primary site for KRAS signaling is the inner leaflet of the plasma membrane (PM). We previously reported that oxanthroquinone G01 (G01) inhibited KRAS PM localization and blocked KRAS signaling. In this study, we identified acylpeptide hydrolase (APEH) as a molecular target of G01. APEH formed a...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6703705/ https://ncbi.nlm.nih.gov/pubmed/31266814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.232132 |
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