Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues

Iron-sulfur (Fe-S) clusters are necessary for the proper functioning of numerous metalloproteins. Fe-S cluster (Isc) and sulfur utilization factor (Suf) pathways are the key biosynthetic routes responsible for generating these Fe-S cluster prosthetic groups in Escherichia coli. Although Isc dominate...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Blahut, Matthew, Wise, Courtney E., Bruno, Michael R., Dong, Guangchao, Makris, Thomas M., Frantom, Patrick A., Dunkle, Jack A., Outten, F. Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699847/
https://ncbi.nlm.nih.gov/pubmed/31248989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009471
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