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Cancer classification and pathway discovery using nonnegative matrix factorization

OBJECTIVES: Extracting genetic information from a full range of sequencing data is important for understanding disease. We propose a novel method to effectively explore the landscape of genetic mutations and aggregate them to predict cancer type. DESIGN: We applied non-smooth non-negative matrix fac...

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Détails bibliographiques
Publié dans:J Biomed Inform
Auteurs principaux: Zeng, Zexian, Vo, Andy H, Mao, Chengsheng, Clare, Susan E, Khan, Seema A, Luo, Yuan
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697569/
https://ncbi.nlm.nih.gov/pubmed/31271844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbi.2019.103247
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