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Construction of a One-Vector Multiplex CRISPR/Cas9 Editing System to Inhibit Nucleopolyhedrovirus Replication in Silkworms

Recently the developed single guide (sg)RNA-guided clustered regularly interspaced short palindromic repeats/associated protein 9 nuclease (CRISPR/Cas9) technology has opened a new avenue for antiviral therapy. The CRISPR/Cas9 system uniquely allows targeting of multiple genome sites simultaneously....

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Bibliografski detalji
Izdano u:Virol Sin
Glavni autori: Dong, Zhanqi, Qin, Qi, Hu, Zhigang, Chen, Peng, Huang, Liang, Zhang, Xinling, Tian, Ting, Lu, Cheng, Pan, Minhui
Format: Artigo
Jezik:Inglês
Izdano: Springer Singapore 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687805/
https://ncbi.nlm.nih.gov/pubmed/31218589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-019-00121-4
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