(1)H HR-MAS NMR-Based Metabolomics of Cancer Cells in Response to Treatment with the Diruthenium Trithiolato Complex [(p-MeC(6)H(4)(i)Pr)(2)Ru(2)(SC(6)H(4)-p-Bu(t))(3)](+) (DiRu-1)

The trithiolato bridged diruthenium complex DiRu-1 [(p-MeC(6)H(4)(i)Pr)(2)Ru(2)(SC(6)H(4)-p-Bu(t))(3)](+) is highly cytotoxic against various cancer cell lines, but its exact mode of action remains unknown. The present (1)H HR-MAS NMR-based metabolomic study was performed on ovarian cancer cell line...

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Detalhes bibliográficos
Publicado no:Metabolites
Main Authors: Primasová, Hedvika, Paul, Lydia E. H., Diserens, Gaëlle, Primasová, Ester, Vermathen, Peter, Vermathen, Martina, Furrer, Julien
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680816/
https://ncbi.nlm.nih.gov/pubmed/31323867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9070146
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