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Ethanol exposure impairs AMPK signaling and phagocytosis in human alveolar macrophages: Role of ethanol metabolism

BACKGROUND: Chronic alcohol consumption impairs alveolar macrophage’s (AM) function, and increases risk for developing lung infection and pneumonia. However, the mechanism and metabolic basis of alcohol-induced AM dysfunction leading to lung infection are not well defined, but may include altered et...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Kaphalia, Lata, Srinivasan, Mukund P., Kakumanu, Ramu D., Kaphalia, Bhupendra S., Calhoun, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679779/
https://ncbi.nlm.nih.gov/pubmed/31211863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14131
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