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Histone-deacetylase inhibition sensitizes PD1 blockade–resistant B-cell lymphomas
PD1-blockade is effective in a subset of B-cell lymphoma patients (e.g., classical-Hodgkin lymphomas); however, most patients do not respond to anti-PD1 therapy. To study PD1-resistance, we used an isoform-selective histone-deacetylase-inhibitor (HDACi) (OKI-179), and a mouse mature B-cell lymphoma,...
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| Publicado no: | Cancer Immunol Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6679731/ https://ncbi.nlm.nih.gov/pubmed/31235619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0875 |
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