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Attenuation of Thrombin-Mediated Fibrin Formation via Changes in Fibrinogen Conformation Induced by Reaction with S-nitroso-N-acetylpenicillamine, but not S-nitrosoglutathione

Previous work in a 4 h rabbit thrombogenicity model has shown that a nitric oxide- (NO) generating polymer extracorporeal circuits (ECC) with infusion of S-nitroso-N-acetyl-penicillamine (SNAP) preserved platelets eventhough platelets were activated as shown by an increase in the glycoprotein, p-sel...

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Détails bibliographiques
Publié dans:J Mater Chem B
Auteurs principaux: Major, Terry C, Brisbois, Elizabeth J, Meyerhoff, Mark E, Bartlett, Robert H
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675453/
https://ncbi.nlm.nih.gov/pubmed/31372222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C8TB02103A
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