Differential Regulation of the Serotonin Transporter Gene by Lithium Is Mediated by Transcription Factors, CCCTC Binding Protein and Y-Box Binding Protein 1, through the Polymorphic Intron 2 Variable Number Tandem Repeat

The serotoninergic pathways are possible targets for the action of lithium, a therapeutic agent for treatment of bipolar affective disorders. This study aimed to investigate the molecular mechanisms regulating human serotonin transporter gene (SLC6A4) expression by lithium and, specifically, the rol...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Roberts, Julian, Scott, Alison C., Howard, Mark R., Breen, Gerome, Bubb, Vivien J., Klenova, Elena, Quinn, John P.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672559/
https://ncbi.nlm.nih.gov/pubmed/17360901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0892-06.2007
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