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Metal-Templated Assembly of Cyclopropane-Fused Diazepanones and Diazecanones via exo-trig Nucleophilic Cyclization of Cyclopropenes with Tethered Carbamates

A strain-release-driven, cation-templated nucleophilic 7- and 8-exotrig-cyclization of tethered Boc-protected amines to cyclopropenes is described. The featured reaction proceeds in diastereo- and regioselective fashion and allows for preparation of the corresponding 2,5-diazabicyclo[5.1.0]octan-6-o...

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Dades bibliogràfiques
Publicat a:J Org Chem
Autors principals: Maslivetc, Vladimir A., Frolova, Liliya V., Rogelj, Snezna, Maslivetc, Anna A., Rubina, Marina, Rubin, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667834/
https://ncbi.nlm.nih.gov/pubmed/30354138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b02062
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