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Regulation of splicing enhancer activities by RNA secondary structures
In this report, we studied the effect of RNA structures on the activity of exonic splicing enhancers on the SMN1 minigene model by engineering known ESEs into different positions of stable hairpins. We found that as short as 7-bp stem is sufficient to abolish the enhancer activity. When placing ESEs...
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| Publicado no: | FEBS Lett |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6644664/ https://ncbi.nlm.nih.gov/pubmed/20888818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.09.039 |
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