Metabotropic Glutamate Receptor-Mediated Cell Signaling Pathways Are Altered in a Mouse Model of Huntington's Disease

Huntington's disease (HD) is an autosomal-dominant neurodegenerative disorder caused by a polyglutamine expansion in the huntingtin protein (Htt). Group I metabotropic glutamate receptors (mGluRs) are coupled to G(αq) and play an important role in neuronal survival. We have previously demonstra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ribeiro, Fabiola M., Paquet, Maryse, Ferreira, Lucimar T., Cregan, Tamara, Swan, Patrick, Cregan, Sean P., Ferguson, Stephen S. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632544/
https://ncbi.nlm.nih.gov/pubmed/20053912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4974-09.2010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados