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The role of hypoxia-inducible factors in metabolic diseases
Hypoxia-inducible factors (HIFs), a family of transcription factors activated by hypoxia, consist of three α-subunits (HIF1α, HIF2α and HIF3α) and one β-subunit (HIF1β), which serves as a heterodimerization partner of the HIFα subunits. HIFα subunits are stabilized from constitutive degradation by h...
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| Veröffentlicht in: | Nat Rev Endocrinol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6624429/ https://ncbi.nlm.nih.gov/pubmed/30275460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41574-018-0096-z |
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