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Expression of a CARD Slows the Retinal Degeneration of a Geographic Atrophy Mouse Model
Age-related macular degeneration (AMD) has been linked to oxidative damage and para-inflammation, an activation of inflammasome signaling in the retinal pigment epithelium (RPE) and the underlying choriocapillaris. Herein, we tested the efficacy of a gene-delivered caspase-1 inhibitor in controlling...
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| Publicat a: | Mol Ther Methods Clin Dev |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Gene & Cell Therapy
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6624323/ https://ncbi.nlm.nih.gov/pubmed/31334304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.06.001 |
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