Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis

Sepsis costs the healthcare system $23 billion annually and has a mortality rate between 10 and 40%. An early indication of sepsis is the onset of hyperglycemia, which is the result of sepsis-induced insulin resistance in skeletal muscle. Previous investigations have focused on events in the myocyte...

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Dades bibliogràfiques
Publicat a:Am J Physiol Endocrinol Metab
Autors principals: Mignemi, Nicholas A., McClatchey, P. Mason, Kilchrist, Kameron V., Williams, Ian M., Millis, Bryan A., Syring, Kristen E., Duvall, Craig L., Wasserman, David H., McGuinness, Owen P.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620574/
https://ncbi.nlm.nih.gov/pubmed/30860883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00501.2018
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