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Conformational change within the extracellular domain of B cell receptor in B cell activation upon antigen binding

B lymphocytes use B cell receptors (BCRs) to recognize antigens. It is still not clear how BCR transduces antigen-specific physical signals upon binding across cell membrane for the conversion to chemical signals, triggering downstream signaling cascades. It is hypothesized that through a series of...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Shen, Zhixun, Liu, Sichen, Li, Xinxin, Wan, Zhengpeng, Mao, Youxiang, Chen, Chunlai, Liu, Wanli
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620044/
https://ncbi.nlm.nih.gov/pubmed/31290744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42271
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