Tumor mutational burden standardization initiatives: Recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy treatment decisions

Characterization of tumors utilizing next‐generation sequencing methods, including assessment of the number of somatic mutations (tumor mutational burden [TMB]), is currently at the forefront of the field of personalized medicine. Recent clinical studies have associated high TMB with improved patien...

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Udgivet i:Genes Chromosomes Cancer
Main Authors: Stenzinger, Albrecht, Allen, Jeffrey D., Maas, Jörg, Stewart, Mark D., Merino, Diana M., Wempe, Madison M., Dietel, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618007/
https://ncbi.nlm.nih.gov/pubmed/30664300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22733
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