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Identification of an Alternating-Access Dynamics Mutant of EmrE with Impaired Transport

Proteins that perform active transport must alternate the access of a binding site, first to one side of a membrane and then to the other, resulting in the transport of bound substrates across the membrane. To better understand this process, we sought to identify mutants of the small multidrug resis...

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Dades bibliogràfiques
Publicat a:J Mol Biol
Autors principals: Wu, Chao, Wynne, Samantha A., Thomas, Nathan E., Uhlemann, Eva-Maria, Tate, Christopher G., Henzler-Wildman, Katherine A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599891/
https://ncbi.nlm.nih.gov/pubmed/31158365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.05.035
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