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Activation of aryl hydrocarbon receptor regulates the LPS/IFNγ-induced inflammatory response by inducing ubiquitin-proteosomal and lysosomal degradation of RelA/p65

Several studies have identified the aryl hydrocarbon receptor (AhR) as a negative regulator of the innate and adaptive immune responses. However, the molecular mechanisms by which this transcription factor exerts such modulatory effects are not well understood. Interaction between AhR and RelA/p65 h...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Domínguez-Acosta, O., Vega, L., Estrada-Muñiz, E., Rodríguez, M.S., Gonzalez, F.J., Elizondo, G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594173/
https://ncbi.nlm.nih.gov/pubmed/29935959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.06.016
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