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bax Deficiency Prevents the Increased Cell Death of Immature Neurons in bcl-x-Deficient Mice

The intracellular balance between pro- and antiapoptotic members of the Bcl-2 gene family is thought to regulate cell death. Targeted disruption of bcl-x, a death repressing member, causes massive cell death of immature neurons in the developing mouse CNS, whereas targeted disruption of bax, a proap...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Shindler, Kenneth S., Latham, Cecelia B., Roth, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573662/
https://ncbi.nlm.nih.gov/pubmed/9096145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-09-03112.1997
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