Down-regulation of cell membrane localized NTCP expression in proliferating hepatocytes prevents hepatitis B virus infection

Hepatocyte proliferation could result in the loss of covalently closed circular DNA (cccDNA) and the emergence of cccDNA-cleared nascent hepatocytes, which appear refractory to hepatitis B virus (HBV) reinfection with unknown mechanism(s). Sodium taurocholate cotransporting polypeptide (NTCP) is the...

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Pubblicato in:Emerg Microbes Infect
Autori principali: Yan, Ying, Allweiss, Lena, Yang, Danli, Kang, Jingting, Wang, Jianwen, Qian, Xiangjun, Zhang, Ting, Liu, Hui, Wang, Lu, Liu, Shuhong, Sui, Jianhua, Chen, Xiangmei, Dandri, Maura, Zhao, Jingmin, Lu, Fengmin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567113/
https://ncbi.nlm.nih.gov/pubmed/31179847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2019.1625728
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