Optimization of an ex vivo gene transfer to the hamstrings tendons muscle remnants: potential for genetic enhancement of bone healing

AIM: To assess whether an adenoviral vector carrying the bone morphogenetic protein genes (Ad.BMP-2) can transduce human muscle tissue and direct it toward osteogenic differentiation within one hour. METHODS: This in vitro study, performed at the Department of Molecular Biology, Faculty of Science,...

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Vydáno v:Croat Med J
Hlavní autoři: Rod, Eduard, Matić, Igor, Antunović, Maja, Vetma, Vesna, Pavičić, Ivan, Hudetz, Damir, Marijanović, Inga, Primorac, Dragan, Ivković, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: Croatian Medical Schools 2019
Témata:
11th ISABS CONFERENCE
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563169/
https://ncbi.nlm.nih.gov/pubmed/31187947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3325/cmj.2019.60.201
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