Serotonin regulates mitochondrial biogenesis and function in rodent cortical neurons via the 5-HT(2A) receptor and SIRT1–PGC-1α axis

Mitochondria in neurons, in addition to their primary role in bioenergetics, also contribute to specialized functions, including regulation of synaptic transmission, Ca(2+) homeostasis, neuronal excitability, and stress adaptation. However, the factors that influence mitochondrial biogenesis and fun...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fanibunda, Sashaina E., Deb, Sukrita, Maniyadath, Babukrishna, Tiwari, Praachi, Ghai, Utkarsha, Gupta, Samir, Figueiredo, Dwight, Weisstaub, Noelia, Gingrich, Jay A., Vaidya, Ashok D. B., Kolthur-Seetharam, Ullas, Vaidya, Vidita A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561197/
https://ncbi.nlm.nih.gov/pubmed/31072928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821332116
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