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NMR Reveals that GU Base Pairs Flanking Internal Loops can Adopt Diverse Structures
RNA thermodynamics play an important role in determining the 2D and 3D structures of RNA. Internal loops of the sequence, 5’-GMNU/3’-UNMG, are relatively unstable thermodynamically. Here, five GU flanked 2×2 nucleotide internal loops were structurally investigated in order to reveal determinants for...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6559796/ https://ncbi.nlm.nih.gov/pubmed/30702283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01027 |
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