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Esterase-Triggered Self-Immolative Thiocarbamates Provide Insights into COS Cytotoxicity

Hydrogen sulfide (H(2)S) is an important gasotransmitter and biomolecule, and many synthetic small-molecule H(2)S donors have been developed for H(2)S-related research. One important class of triggerable H(2)S donors are self-immolative thiocarbamates, which function by releasing carbonyl sulfide (C...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Levinn, Carolyn M., Steiger, Andrea K., Pluth, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534120/
https://ncbi.nlm.nih.gov/pubmed/30640440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00981
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