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Eukaryotic initiation factor 4E-binding protein as an oncogene in breast cancer

BACKGROUND: Eukaryotic Initiation Factor 4E-Binding Protein (EIF4EBP1, 4EBP1) is overexpressed in many human cancers including breast cancer, yet the role of 4EBP1 in breast cancer remains understudied. Despite the known role of 4EBP1 as a negative regulator of cap-dependent protein translation, 4EB...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Rutkovsky, Alexandria C., Yeh, Elizabeth S., Guest, Stephen T., Findlay, Victoria J., Muise-Helmericks, Robin C., Armeson, Kent, Ethier, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533768/
https://ncbi.nlm.nih.gov/pubmed/31122207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5667-4
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