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A novel mutation in FBN1 gene in autosomal dominant Marfan syndrome and macular degeneration in a Chinese consanguineous family

AIM: To report a novel mutation in FBN1 gene in a Chinese consanguineous family with common Marfan syndrome (MFS) phenotype and an unusual bilateral macular degeneration. METHODS: Ophthalmic, cardiovascular and systemic examinations were performed, and genomic DNA extracted from all living family me...

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Vydáno v:Int J Ophthalmol
Hlavní autoři: Ouyang, Ping-Bo, Zhao, Yuan, Peng, Ying-Qian, Zhang, Lu-Si, Cao, Jian, Li, Yun
Médium: Artigo
Jazyk:Inglês
Vydáno: International Journal of Ophthalmology Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520272/
https://ncbi.nlm.nih.gov/pubmed/31131229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2019.05.05
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