Unveiling the Efficacy, Safety, and Tolerability of Anti-Interleukin-1 Treatment in Monogenic and Multifactorial Autoinflammatory Diseases

Autoinflammatory diseases (AIDs) are heterogeneous disorders characterized by dysregulation in the inflammasome, a large intracellular multiprotein platform, leading to overproduction of interleukin-1(IL-1)β that plays a predominant pathogenic role in such diseases. Appropriate treatment is crucial,...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Bettiol, Alessandra, Lopalco, Giuseppe, Emmi, Giacomo, Cantarini, Luca, Urban, Maria Letizia, Vitale, Antonio, Denora, Nunzio, Lopalco, Antonio, Cutrignelli, Annalisa, Lopedota, Angela, Venerito, Vincenzo, Fornaro, Marco, Vannacci, Alfredo, Rigante, Donato, Cimaz, Rolando, Iannone, Florenzo
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514653/
https://ncbi.nlm.nih.gov/pubmed/30999610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081898
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