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Fine-particulate matter aggravates cigarette smoke extract–induced airway inflammation via Wnt5a–ERK pathway in COPD

BACKGROUND: Exposure to environmental particulate matter (PM) ≤2.5 μm in diameter (PM(2.5)) and smoking are common contributors to COPD, and pertinent research implicates both factors in pulmonary inflammation. Using in vivo mouse and in vitro human cellular models, we investigated the joint impact...

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Bibliografiske detaljer
Udgivet i:Int J Chron Obstruct Pulmon Dis
Main Authors: Wang, Zhihua, Zhao, Junling, Wang, Ting, Du, Xiaohui, Xie, Jungang
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512785/
https://ncbi.nlm.nih.gov/pubmed/31190784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S195794
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