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Soluble expression of proteins correlates with a lack of positively-charged surface
Prediction of protein solubility is gaining importance with the growing use of protein molecules as therapeutics, and ongoing requirements for high level expression. We have investigated protein surface features that correlate with insolubility. Non-polar surface patches associate to some degree wit...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6506438/ https://ncbi.nlm.nih.gov/pubmed/24276756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03333 |
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