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Thionoesters: A Native Chemical Ligation-Inspired Approach to Cysteine-Triggered H(2)S Donors
Native chemical ligation (NCL) is a simple, widely-used, and powerful synthetic tool to ligate N-terminal cysteine residues and C-terminal α-thioesters via a thermodynamically-stable amide bond. Building on this well-established reactivity, as well as advancing our interests in the chemical biology...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6504978/ https://ncbi.nlm.nih.gov/pubmed/30230325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b07268 |
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