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Apatinib preferentially inhibits PC9 gefitinib-resistant cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway

BACKGROUND: Lung cancer is one of the most common and deadly tumors around the world. Targeted therapy for patients with certain mutations, especially by use of tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR), has provided significant benefit to patients. However,...

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Bibliografiske detaljer
Udgivet i:Cancer Cell Int
Main Authors: Song, Yong-An, Ma, Ting, Zhang, Xue-Yan, Cheng, Xiang-Song, Olajuyin, Ayobami-Matthew, Sun, Zhi-Fu, Zhang, Xiao-Ju
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498592/
https://ncbi.nlm.nih.gov/pubmed/31073278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0836-8
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