Tissue Repair Signals and In Vitro Culture: Inflammatory Cytokine TNFα Promotes the Expansion of Primary Hepatocytes in 3D Culture

In the healthy adult liver, most hepatocytes proliferate minimally. Yet upon physical or chemical injury to the liver, hepatocytes intensely proliferate in vivo under the direction of multiple extracellular cues, including Wnt and pro-inflammatory signals. Currently, liver organoids can be readily g...

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Publicado no:Cell
Main Authors: Peng, Weng Chuan, Logan, Catriona, Fish, Matt, Anbarchian, Teni, Aguisanda, Francis, Alvarez, Adrian, Wu, Peng, Jin, Yinhua, Zhu, Junjie, Li, Bin, Grompe, Markus, Wang, Bruce, Nusse, Roel
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497386/
https://ncbi.nlm.nih.gov/pubmed/30500539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.012
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