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Selection of cost-effective yet chemically diverse pathways from the networks of computer-generated retrosynthetic plans

As the programs for computer-aided retrosynthetic design come of age, they are no longer identifying just one or few synthetic routes but a multitude of chemically plausible syntheses, together forming large, directed graphs of solutions. An important problem then emerges: how to select from these g...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Badowski, Tomasz, Molga, Karol, Grzybowski, Bartosz A.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495691/
https://ncbi.nlm.nih.gov/pubmed/31123574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05611k
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