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Novel biomanufacturing platform for large-scale and high-quality human T cells production

The adoptive transfer of human T cells or genetically-engineered T cells with cancer-targeting receptors has shown tremendous promise for eradicating tumors in clinical trials. The objective of this study was to develop a novel T cell biomanufacturing platform using stirred-tank bioreactor for large...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Eng
Hauptverfasser: Ou, Jianfa, Si, Yingnan, Tang, Yawen, Salzer, Grace E., Lu, Yun, Kim, Seulhee, Qin, Hongwei, Zhou, Lufang, Liu, Xiaoguang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480708/
https://ncbi.nlm.nih.gov/pubmed/31044002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0167-2
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