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Oscillatory shear potentiates latent TGF-β1 activation more than steady shear as demonstrated by a novel force generator
Cardiovascular mechanical stresses trigger physiological and pathological cellular reactions including secretion of Transforming Growth Factor β1 ubiquitously in a latent form (LTGF-β1). While complex shear stresses can activate LTGF-β1, the mechanisms underlying LTGF-β1 activation remain unclear. W...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6465594/ https://ncbi.nlm.nih.gov/pubmed/30988341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42302-x |
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