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The interaction between IKKα and LC3 promotes type I interferon production through the TLR9-containing LAPosome
Toll-like receptor 9 (TLR9) recognizes DNA in endosomes and activates distinct signaling pathways to stimulate the production of proinflammatory cytokines and type I interferons (IFN). The assembly of signaling platforms on microtubule-associated proteins 1A/1B light chain 3B (LC3)-decorated endosom...
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| Publicado no: | Sci Signal |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462218/ https://ncbi.nlm.nih.gov/pubmed/29717061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan4144 |
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