Vaccine Generation of Protective Ebola Antibodies and Identification of Conserved B-Cell Signatures

We recently identified a single potently neutralizing monoclonal antibody (mAb), mAb114, isolated from a human survivor of natural Zaire ebolavirus (EBOV) infection, which fully protects nonhuman primates (NHPs) against lethal EBOV challenge. To evaluate the ability of vaccination to generate mAbs s...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Cagigi, Alberto, Misasi, John, Ploquin, Aurélie, Stanley, Daphne A, Ambrozak, David, Tsybovsky, Yaroslav, Mason, Rosemarie D, Roederer, Mario, Sullivan, Nancy J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Supplement Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455927/
https://ncbi.nlm.nih.gov/pubmed/30010811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy333
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