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40.3 TARGETING NMDAR HYPOFUNCTION DURING EARLY DEVELOPMENT FOR THE PREVENTION OF SCHIZOPHRENIA PHENOTYPES IN ADULTHOOD IN THE MAM MODEL
BACKGROUND: Glutamate hypofunction has been a prominent hypothesis in the understanding of schizophrenia (SCZ) pathology. Particularly, the N-methyl-D-aspartate receptor (NMDAR), a major glutamate receptor subtype, demonstrates alterations in post-mortem studies, and prefrontal glutamatergic hypofun...
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| Veröffentlicht in: | Schizophr Bull |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6455813/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz022.166 |
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